Recombinant人PAIP2 protein (ab89367)

概述

  • 产品名称Recombinant人PAIP2 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab89367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab89367 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • PABP-interacting protein 2
    • PAIP-2
    • PAIP2
    • PAIP2_HUMAN
    • poly(A) binding protein interacting protein 2
    • Poly(A)-binding protein-interacting protein 2
    • Polyadenylate-binding protein-interacting protein 2
    see all
  • 功能Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
  • 序列相似性Belongs to the PAIP2 family.
  • 结构域Only the PABPC1-interacting motif-1 (PAM1) interferes with the binding of PABPC1 to poly(A) RNA and translation initiation.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human PAIP2 protein 图像

  • 15% SDS-PAGE showing ab89367 (3µg).

Recombinant Human PAIP2 protein (ab89367)参考文献

ab89367 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"