Recombinant人PAI1 + PLAT protein (ab92549)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab92549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Human PAI1 stable mutant is reacted with an excess of Human sc-PLAT at physiological pH. The resulting 1:1 molar complex is purified from the remaining PLAT by cobalt metal affinity chromatography resin.
  • 形式Liquid
  • 补充说明Spectrophotometric data: e0.1%=1.56
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.4M HEPES, 0.1M Sodium chloride, pH 7.4

常规信息

  • 别名
    • Alteplase
    • PAI 1
    • PLANH1
    • Plasminogen activator inhibitor 1
    • PLAT
    • Reteplase
    • t PA
    • t plasminogen activator
    • tPA
    see all
  • 相关性PAI1 acts as "bait" for tissue plasminogen activator (TPA), urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. TPA: This converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.
  • 细胞定位Secreted protein; extracellular space.

Recombinant Human PAI1 + PLAT protein 图像

  • 10% SDS-PAGE
    Lane 1: ab92549 (3µg) Reduced
    Lane 2: ab92549 (3µg) Non-Reduced

Recombinant Human PAI1 + PLAT protein (ab92549)参考文献

ab92549 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab92549.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"