Recombinant人PAFR +Gia1ß1?2 fusion co-expressed protein (ab90726)

概述

  • 产品名称Recombinant人PAFR +Gia1ß1?2 fusion co-expressed protein
  • 蛋白长度Full length protein
  • 描述
    Recombinant人PAFR +Giα1β1γ2 fusion co-expressed protein

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab90726 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

常规信息

  • 别名
    • Adenylate cyclase inhibiting G alpha protein
    • Beta subunit signal transducing proteins GS/GI
    • G gamma I
    • G protein beta 1 subunit
    • Gi
    • Gi1 protein alpha subunit
    • GNAI1
    • GNB1
    • GNG2
    • Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1
    • Guanine nucleotide binding protein (G protein) beta polypeptide 1
    • Guanine nucleotide binding protein (G protein) gamma 2
    • Guanine nucleotide binding protein beta 1 subunit
    • Guanine nucleotide binding protein G(i) subunit alpha 1
    • Guanine nucleotide binding protein G(I)/G(O) gamma 2 subunit
    • Guanine nucleotide binding protein G(I)/G(S)/G(O) subunit gamma 2
    • Guanine nucleotide binding protein G(I)/G(S)/G(T) beta subunit 1
    • Guanine nucleotide binding protein G(I)/G(S)/G(T) subunit beta 1
    • Guanine nucleotide binding protein gamma 2
    • PAF R
    • PAFR
    • Platelet activating factor receptor
    • PTAFR
    • Transducin beta chain 1
    see all
  • 相关性Platelet-activating factor (PAF) is a pro-inflammatory lipid mediator possessing a unique 1-O-alkyl-2-acetylsnglycero-3-phosphocholine backbone. The PAF receptor (PAFR), which belongs to the superfamily of seven transmembrane (7TM), G-protein coupled receptors (GPCRs), transduces pleiotropic functions including cell motility, smooth muscle contraction, and synthesisand release of mediators and cytokines via multiple heterotrimeric G-proteins. Pharmacological studies have suggested that PAF functions in a variety of settings including allergy, inflammation, neural functions, reproduction, and atherosclerosis. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
  • 细胞定位PAFR: Cell membrane; Multi-pass membrane protein GNG2 Cell membrane; Lipid-anchor; Cytoplasmic side

Recombinant Human PAFR +Gia1ß1?2 fusion co-expressed protein (ab90726)参考文献

ab90726 has not yet been referenced specifically in any publications.

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