概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQL LILLYFVWYVFIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVK PPEGGSVFSIITRVEATHSQTQGTCPESIRVHNATCLSDADCVAGELDML GNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIK NSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGE SFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALT SVGVGSFLCDWILLTFMNKNKVYSHKKFDKMVDTPASEPAQASTPTDPKG LAQL
    • 分子量
      71 kDa including tags
    • 氨基酸
      1 to 404

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技术指标

Our Abpromise guarantee covers the use of ab132031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ATP receptor
    • MGC129601
    • P2RX 2
    • P2RX2
    • P2RX2_HUMAN
    • P2X purinoceptor 2
    • P2X Receptor subunit 2
    • P2X2
    • P2X2a
    • Purinergic receptor
    • Purinergic receptor P2X ligand gated ion channel 2
    • Purinergic receptor P2X2 isoform A
    • Purinergic receptor P2X2 isoform B
    • Purinergic receptor P2X2 isoform C
    • Purinergic receptor P2X2 isoform D
    • Purinergic receptor P2X2 isoform H
    • Purinergic receptor P2X2 isoform I
    see all
  • 功能
    Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • 疾病相关
    Deafness, autosomal dominant, 41
  • 序列相似性
    Belongs to the P2X receptor family.
  • 细胞定位
    Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab132031 at approximately 71.2 kDa.

文献

ab132031 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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