- 来源Escherichia coli
- 序列MGSSHHHHHHSSGLVPRGSHMAEPWGNELASAAARGDLEQLTSLLQNNVN VNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARA GFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
- 分子量21 kDa including tags
- 氨基酸1 to 168
- 标签His tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 95
ab119460 was purified using conventional chromatography techniques.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.32% Tris HCl, 0.03% DTT, 10% Glycerol, 1.17% Sodium chloride
- CDK6 inhibitor p18
- CDKN 2C
- CDKN 6
- 功能Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
- 组织特异性Highest levels found in skeletal muscle. Also found in pancreas and heart.
- 序列相似性Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Contains 4 ANK repeats.
Information by UniProt
Recombinant Human p18 INK4c protein 图像
Recombinant Human p18 INK4c protein (ab119460)参考文献
has not yet been referenced specifically in any publications.
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