Recombinant人NUDT3 protein (ab103915)

概述

  • 产品名称Recombinant人NUDT3 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO95989
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS VAAVREVCEE AGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTY SVSAQSSMSG IR
    • 分子量22 kDa including tags
    • 氨基酸1 to 172
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    Purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 5mM DTT, 200mM Sodium chloride, 20mM Tris HCl, pH 8

常规信息

  • 别名
    • 5''''-P1
    • Diadenosine 5' 5''' P1 P6 hexaphosphate hydrolase 1
    • Diadenosine 5''
    • Diphosphoinositol polyphosphate phosphohydrolase
    • Diphosphoinositol polyphosphate phosphohydrolase 1
    • DIPP
    • DIPP 1
    • DIPP-1
    • DIPP1
    • Nucleoside diphosphate linked moiety X motif 3
    • Nucleoside diphosphate-linked moiety X motif 3
    • Nudix (nucleoside diphosphate linked moiety X) type motif 3
    • Nudix motif 3
    • Nudix type motif 3
    • NUDT 3
    • Nudt3
    • NUDT3_HUMAN
    • P6-hexaphosphate hydrolase 1
    see all
  • 功能Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
  • 组织特异性Widely expressed. Expressed at higher level in brain, heart, pancreas and liver. Also expressed in placenta, lung and kidney.
  • 序列相似性Belongs to the Nudix hydrolase family. DIPP subfamily.
    Contains 1 nudix hydrolase domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human NUDT3 protein 图像

  • 15% SDS-PAGE analysis of ab103915 (3 µg).

Recombinant Human NUDT3 protein (ab103915)参考文献

ab103915 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"