Recombinant人NUDT10 protein (ab125779)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ8NFP7
    • 种属Human
    • 序列MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDPLEHHHH HH
    • 分子量20 kDa including tags
    • 氨基酸1 to 164
    • 标签His tag C-Terminus
    • 额外的序列信息NUDT10 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-164 a.a.) and having a molecular mass of 19.5kDa.

技术指标

Our Abpromise guarantee covers the use of ab125779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab125779 was purified by proprietary chromatographic techniques and filter sterilized.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • 5'''-P1
    • APS 2
    • APS2
    • Diadenosine 5'
    • Diadenosine 5' 5''' P1 P6 hexaphosphate hydrolase 3 alpha
    • Diadenosine hexaphosphate hydrolase (AMP-forming)
    • Diphosphoinositol polyphosphate phosphohydrolase 3, alpha
    • Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
    • Diphosphoinositol polyphosphate phosphohydrolase type 3 alpha
    • DIPP 3 alpha
    • DIPP 3a
    • DIPP-3-alpha
    • DIPP3 alpha
    • DIPP3-alpha
    • DIPP3a
    • hAps 2
    • hAps2
    • hDIPP3alpha
    • Nucleoside diphosphate linked moiety X motif 10
    • Nucleoside diphosphate-linked moiety X motif 10
    • NUD10_HUMAN
    • Nudix (nucleoside diphosphate linked moiety X) type motif 10
    • Nudix motif 10
    • Nudix type motif 10
    • NUDT 10
    • NUDT10
    • P6-hexaphosphate hydrolase 3-alpha
    see all
  • 功能Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
  • 组织特异性Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely expressed.
  • 序列相似性Belongs to the Nudix hydrolase family. DIPP subfamily.
    Contains 1 nudix hydrolase domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human NUDT10 protein (ab125779)参考文献

ab125779 has not yet been referenced specifically in any publications.

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