Recombinant人NTH1 protein (ab113607)

概述

  • 产品名称Recombinant人NTH1 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP78549
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMCSPQESGMTALSARMLTRSRSLGPGAGPR GCREEPGPLRRREAAAEARKSHSPVKRPRKAQRLRVAYEGSDSEKGEGAE PLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVRRY QVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAW GTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEING LLVGFGQQTCLPVHPRCHACLNQALCPAAQGL
    • 分子量37 kDa including tags
    • 氨基酸1 to 312
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 80 % SDS-PAGE.
    ab113607 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase
    • DNA glycoslyase/AP lyase
    • Endonuclease III like protein 1
    • Endonuclease III-like protein 1
    • hNTH1
    • NTH 1
    • NTH endonuclease III Like 1
    • nth endonuclease III like 1 (E. coli)
    • NTH1
    • NTHL 1
    • Nthl1
    • NTHL1_HUMAN
    • OCTS 3
    • OCTS3
    see all
  • 功能Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
  • 组织特异性Widely expressed with highest levels in heart and lowest levels in lung and liver.
  • 序列相似性Belongs to the Nth/MutY family.
  • 发展阶段Expression levels are regulated during the cell cycle with increased levels during early and mid S-phase.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human NTH1 protein 图像

  • 15% SDS-PAGE analysis of ab113607 (3µg)

Recombinant Human NTH1 protein (ab113607)参考文献

ab113607 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. I heard back from the lab that ab113607 is not denatured.  I hope this information helps.  Please contact us with any other questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"