重组人NR5A2 / LRH1蛋白(ab81844)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% Immunogen affinity purified
- Suitable for: WB, GSA
描述
-
产品名称
重组人NR5A2 / LRH1蛋白
参阅全部 NR5A2 / LRH1 蛋白酶 -
纯度
> 95 % Immunogen affinity purified.
Purified LRH-1 protein is greater than 95% homogeneous and contains no detectable protease, DNase, and RNase activity. -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human
-
技术指标
Our Abpromise guarantee covers the use of ab81844 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Western blot
Gel Supershift Assays
EMSA
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.9
Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol (glycerin, glycerine)
常规信息
-
别名
- Alpha-1-fetoprotein transcription factor
- B1-binding factor
- B1F
see all -
功能
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. -
组织特异性
Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells. -
序列相似性
Belongs to the nuclear hormone receptor family. NR5 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab81844 被引用在 1 文献中.
- Hughes CHK et al. NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy. Reproduction 161:173-182 (2021). PubMed: 33320828