重组人NOXA2/p67phox蛋白(ab152557)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTIL KNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQ
    • 分子量
      37 kDa including tags
    • 氨基酸
      1 to 100

技术指标

Our Abpromise guarantee covers the use of ab152557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 67 kDa neutrophil oxidase factor
    • Chronic granulomatous disease autosomal 2
    • FLJ93058
    • NADPH oxidase activator 2
    • NCF-2
    • Ncf2
    • NCF2_HUMAN
    • Neutrophil cytosol factor 2
    • Neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
    • Neutrophil NADPH oxidase factor 2
    • NOXA2
    • P67 PHOX
    • p67-phox
    • p67phox
    see all
  • 功能
    NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
  • 疾病相关
    Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2) [MIM:233710]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
  • 序列相似性
    Belongs to the NCF2/NOXA1 family.
    Contains 1 OPR domain.
    Contains 2 SH3 domains.
    Contains 3 TPR repeats.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152557 stained with Coomassie Blue.

文献

ab152557 has not yet been referenced specifically in any publications.

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