Recombinant人Nodal protein (ab114307)

概述

  • 产品名称
    Recombinant人Nodal protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      RCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSML YVDNGRVLLDHHKDMIVEECGC
    • 分子量
      34 kDa including tags
    • 氨基酸
      275 to 346
    • 标签
      GST tag N-Terminus

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05µg/µl
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • HTX5
    • MGC138230
    • Nodal
    • Nodal Growth Differentiation Factor
    • Nodal homolog
    • nodal homolog (mouse)
    • Nodal, Mouse, Homolog
    • NODAL_HUMAN
    see all
  • 功能
    Essential for mesoderm formation and axial patterning during embryonic development.
  • 疾病相关
    Defects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.
  • 序列相似性
    Belongs to the TGF-beta family.
  • 细胞定位
    Secreted.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE image showing ab114307 Stained with Coomassie Blue.

文献

ab114307 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry and your interest in our products.

With regards to our recombinant protein (ab114307), could you please confirm the application(s) you wish to use the product in? I can confirm that this particular recombinant protei...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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