Recombinant人NM23A protein (ab87667)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE

技术指标

Our Abpromise guarantee covers the use of ab87667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab87667 is purified using conventional chromatography techniques. Endotoxin: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 7.5

常规信息

  • 别名
    • AWD
    • AWD, drosophila, homolog of
    • GAAD
    • Granzyme A activated DNase
    • Granzyme A-activated DNase
    • GZMA activated DNase
    • Metastasis inhibition factor NM23
    • NB
    • NBS
    • NDK A
    • NDKA
    • NDKA_HUMAN
    • NDP kinase A
    • NDPK-A
    • NDPKA
    • NM23
    • NM23 long variant, included
    • nm23-H1
    • NM23-M1
    • NM23H1B, included
    • NME/NM23 nucleoside diphosphate kinase 1
    • Nme1
    • NME1-NME2 spliced read-through transcript, included
    • Non-metastatic cells 1, protein (NM23A) expressed in
    • Nonmetastatic cells 1, protein expressed in
    • Nonmetastatic protein 23
    • Nonmetastatic protein 23, homolog 1
    • Nucleoside diphosphate kinase A
    • Tumor metastatic process-associated protein
    see all
  • 功能Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
  • 组织特异性Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
  • 序列相似性Belongs to the NDK family.
  • 细胞定位Cytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
  • Information by UniProt

Recombinant Human NM23A protein 图像

  • 15% SDS-PAGE showing ab87667 at approximately 17.1kDa (3µg).

Recombinant Human NM23A protein (ab87667)参考文献

ab87667 has not yet been referenced specifically in any publications.

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