Recombinant人Nicotinic Acetylcholine Receptor alpha 2 protein (ab114913)

概述

  • 产品名称Recombinant人Nicotinic Acetylcholine Receptor alpha 2 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ15822
    • 种属Human
    • 序列EEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDRLFKHLFRGYNRWARP VPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPAD FGNITSLRVP
    • 分子量38 kDa including tags
    • 氨基酸27 to 136

技术指标

Our Abpromise guarantee covers the use of ab114913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ACHA2_HUMAN
    • AChR
    • Cholinergic receptor nicotinic alpha 2
    • Chrna2
    • Neuronal acetylcholine receptor protein subunit alpha 2
    • Neuronal acetylcholine receptor subunit alpha-2
    see all
  • 功能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 疾病相关Defects in CHRNA2 are the cause of nocturnal frontal lobe epilepsy type 4 (ENFL4) [MIM:610353]. ENFL4 is an autosomal dominant epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-2/CHRNA2 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

Recombinant Human Nicotinic Acetylcholine Receptor alpha 2 protein 图像

  • 12.5% SDS-PAGE showing ab114913 at approximately 37.73kDa.
    Stained with Coomassie Blue.

Recombinant Human Nicotinic Acetylcholine Receptor alpha 2 protein (ab114913)参考文献

ab114913 has not yet been referenced specifically in any publications.

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