The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明Best use within three months from the date of receipt of this protein.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Protein kinase C substrate RC3
Calmodulin binding protein
Neurogranin (protein kinase C substrate)
Protein kinase C substrate
功能Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium.
组织特异性In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease.
序列相似性Belongs to the neurogranin family. Contains 1 collagen-like domain. Contains 1 IQ domain.