Recombinant人Nebulin protein (ab114753)

概述

  • 产品名称Recombinant人Nebulin protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP20929
    • 种属Human
    • 序列NTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTR NMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQH PSNFQFKKLT
    • 分子量38 kDa including tags
    • 氨基酸2108 to 2217

技术指标

Our Abpromise guarantee covers the use of ab114753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • DKFZp686C1456
    • FLJ11505
    • FLJ36536
    • FLJ39568
    • FLJ39584
    • NEB
    • NEB 177D
    • NEB177D
    • NEBU_HUMAN
    • Nebulin
    • NEM 2
    • NEM2
    see all
  • 功能This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Bind and stabilize F-actin.
  • 组织特异性Muscle specific. Located in the thin filament of striated muscle.
  • 疾病相关Defects in NEB are the cause of nemaline myopathy type 2 (NEM2) [MIM:256030]. A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-or rod-like structures in muscle fibers on histologic examination.
  • 序列相似性Contains 178 nebulin repeats.
    Contains 1 SH3 domain.
  • 细胞定位Cytoplasm > myofibril > sarcomere. Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human Nebulin protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114753 at approximately 37.73kDa.

Recombinant Human Nebulin protein (ab114753)参考文献

ab114753 has not yet been referenced specifically in any publications.

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