Recombinant人Ndufs4 protein (ab86684)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MAQDQTQDTQ LITVDEKLDI TTLTGVPEEH IKTRKVRIFV PARNNMQSGV NNTKKWKMEF DTRERWENPL MGWASTADPL SNMVLTFSTK EDAVSFAEKN GWSYDIEERK VPKPKSKSYG ANFSWNKRTR VSTK

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技术指标

Our Abpromise guarantee covers the use of ab86684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab86684 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • AQDQ
    • CI 18
    • CI 18 kDa
    • CI AQDQ
    • CI-18 kDa
    • CI-AQDQ
    • Complex I 18 kDa
    • Complex I AQDQ
    • Complex I-18 kDa
    • Complex I-AQDQ
    • mitochondrial
    • mitochondrial respiratory chain complex I (18 KD subunit)
    • NADH coenzyme Q reductase
    • NADH dehydrogenase
    • NADH dehydrogenase (ubiquinone) Fe S protein 4 18kDa
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 4
    • NADH ubiquinone oxidoreductase 18 kDa subunit
    • NADH-ubiquinone oxidoreductase 18 kDa subunit
    • NDUFS4
    • NDUS4_HUMAN
    see all
  • 功能Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 疾病相关Defects in NDUFS4 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • 序列相似性Belongs to the complex I NDUFS4 subunit family.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt

Recombinant Human Ndufs4 protein 图像

  • 15% SDS-PAGE showing ab86684(3µg).

Recombinant Human Ndufs4 protein (ab86684)参考文献

ab86684 has not yet been referenced specifically in any publications.

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