Recombinant人NDST1 protein (ab116875)

概述

  • 产品名称Recombinant人NDST1 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP52848
    • 种属Human
    • 序列LYGWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQAATPSRTDPLVLV FVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALI
    • 分子量37 kDa including tags
    • 氨基酸38 to 136

相关产品

技术指标

Our Abpromise guarantee covers the use of ab116875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • [Heparan sulfate]-glucosamine N-sulfotransferase 1
    • Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
    • Glucosaminyl N-deacetylase/N-sulfotransferase 1
    • Heparan sulfate N-deacetylase 1
    • Heparan sulfate N-sulfotransferase 1
    • HSNST 1
    • HSST
    • HSST1
    • N-heparan sulfate sulfotransferase 1
    • N-HSST 1
    • NDST-1
    • Ndst1
    • NDST1_HUMAN
    see all
  • 功能Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
  • 组织特异性Widely expressed. Expression is most abundant in heart, liver and pancreas.
  • 通路Glycan metabolism; heparan sulfate biosynthesis.
    Glycan metabolism; heparin biosynthesis.
  • 序列相似性Belongs to the sulfotransferase 1 family. NDST subfamily.
  • 细胞定位Golgi apparatus membrane.
  • Information by UniProt

Recombinant Human NDST1 protein 图像

  • 12.5% SDS-PAGE of ab116875 at approximately 36.52kDa, stained with Coomassie Blue.

Recombinant Human NDST1 protein (ab116875)参考文献

ab116875 has not yet been referenced specifically in any publications.

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