Recombinant人NAGLU protein (ab114822)

概述

  • 产品名称Recombinant人NAGLU protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP54802
    • 种属Human
    • 序列YQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQ QHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPGWVAGS
    • 分子量37 kDa including tags
    • 氨基酸644 to 742

技术指标

Our Abpromise guarantee covers the use of ab114822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Alpha N acetylglucosaminidase
    • alpha N acetylglucosaminidase, lysosomal
    • Alpha-N-acetylglucosaminidase 77 kDa form
    • ANAG
    • ANAG_HUMAN
    • MPS IIIB
    • MPS3B
    • N acetyl alpha glucosaminidase
    • N acetylglucosaminidase, alpha
    • N-acetyl-alpha-glucosaminidase
    • NAG
    • NAGLU
    • UFHSD
    • UFHSD 1
    • UFHSD1
    see all
  • 功能Involved in the degradation of heparan sulfate.
  • 组织特异性Liver, ovary, peripheral blood leukocytes, testis, prostate, spleen, colon, lung, placenta and kidney.
  • 疾病相关Defects in NAGLU are the cause of mucopolysaccharidosis type 3B (MPS3B) [MIM:252920]; also known as Sanfilippo syndrome B. MPS3B is a form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage disease due to impaired degradation of heparan sulfate. MPS3 is characterized by severe central nervous system degeneration, but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologic degeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second or third decade of life.
  • 细胞定位Lysosome.
  • Information by UniProt

Recombinant Human NAGLU protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human NAGLU protein (ab114822)参考文献

ab114822 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"