Recombinant人Nab2 protein (ab116846)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ15742
    • 种属Human
    • 序列DGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLV SHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEA EASRQ
    • 分子量37 kDa including tags
    • 氨基酸421 to 525

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技术指标

Our Abpromise guarantee covers the use of ab116846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • EGR 1 binding protein 2
    • EGR-1-binding protein 2
    • EGR1 binding protein 2
    • MADER
    • Melanoma associated delayed early response protein
    • Melanoma-associated delayed early response protein
    • MGC75085
    • Nab 2
    • nab2
    • NAB2_HUMAN
    • NGFI A binding protein 2
    • NGFI A binding protein 2 (EGR1 binding protein 2)
    • NGFI-A-binding protein 2
    • Protein MADER
    see all
  • 功能Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
  • 组织特异性Widely expressed at low levels. Highly expressed in melanoma cell lines.
  • 序列相似性Belongs to the NAB family.
  • 结构域The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.
    The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
  • 细胞定位Nucleus. Isoform 2 is not localized to the nucleus.
  • Information by UniProt

Recombinant Human Nab2 protein 图像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116846 at approximately 37.18 kDa.

Recombinant Human Nab2 protein (ab116846)参考文献

ab116846 has not yet been referenced specifically in any publications.

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