Recombinant人n-Myc protein (ab114325)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP04198
    • 种属Human
    • 序列MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIW KKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLG GLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSP GAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKR EPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHK ALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTIT VRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKI KSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSS FLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQAR QQQLLKKIEHARTC
    • 分子量77 kDa
    • 氨基酸1 to 464
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab114325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • bHLHe37
    • Class E basic helix-loop-helix protein 37
    • MODED
    • mycn
    • MYCN_HUMAN
    • N myc
    • N myc proto oncogene protein
    • N-myc proto-oncogene protein
    • Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene
    • Neuroblastoma MYC oncogene
    • NMYC
    • NMYC proto oncogene protein
    • ODED
    • Oncogene NMYC
    • pp65/67
    • v myc avian myelocytomatosis viral related oncogene neuroblastoma derived
    • v myc myelocytomatosis viral related oncogene neuroblastoma derived
    see all
  • 功能May function as a transcription factor.
  • 疾病相关Note=Amplification of the N-MYC gene is associated with a variety of human tumors, most frequently neuroblastoma, where the level of amplification appears to increase as the tumor progresses.
    Defects in MYCN are the cause of microcephaly-oculo-digito-esophageal-duodenal syndrome (MODED) [MIM:164280]; also known as oculodigitoesophagoduodenal syndrome (ODED). Microcephaly-oculo-digito-esophageal-duodenal syndrome is characterized by variable combinations of esophageal and duodenal atresias, microcephaly, learning disability and limb malformations. Cardiac and renal malformations, vertebral anomalies, and deafness have also been described.
    Defects in MYCN are the cause of microcephaly and digital abnormalities with normal intelligence (MCPHDANI) [MIM:602585].
  • 序列相似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 发展阶段Expressed during fetal development.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human n-Myc protein 图像

  • SDS-PAGE analysis of ab114325 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human n-Myc protein (ab114325)参考文献

ab114325 has not yet been referenced specifically in any publications.

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