Recombinant人Myostatin Propeptide protein (ab49855)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO14793
    • 种属Human
    • 序列MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
    • 分子量28 kDa
    • 氨基酸23 to 266

技术指标

Our Abpromise guarantee covers the use of ab49855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01–0.04 μg/ml in the presence of 50 ng/ml Myostatin.

  • 应用

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Cmpt
    • GDF-8
    • GDF8_HUMAN
    • Growth/differentiation factor 8
    • MSLHP
    • MSTN
    • MSTN myostatin
    • Myostatin
    • Myostatin Propeptide
    see all
  • 功能Acts specifically as a negative regulator of skeletal muscle growth.
  • 疾病相关Defects in MSTN are the cause of muscle hypertrophy (MSLHP) [MIM:614160]. MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Myostatin Propeptide protein (ab49855)参考文献

ab49855 has not yet been referenced specifically in any publications.

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