Recombinant人Myosin Light Chain 2 protein (ab79185)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD

技术指标

Our Abpromise guarantee covers the use of ab79185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

  • 纯度> 95 % SDS-PAGE.
    ab79185 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 5mM Calcium chloride, 20mM Tris, pH 8.0

常规信息

  • 别名
    • Cardiac myosin light chain-2
    • Cardiac ventricular myosin light chain 2
    • CMH10
    • MLC 2v
    • MLC-2
    • MLC-2v
    • MLC2
    • MLRV_HUMAN
    • MYL 2
    • MYL2
    • Myosin light chain 2 regulatory cardiac slow
    • Myosin light polypeptide 2 regulatory cardiac slow
    • Myosin regulatory light chain 2
    • Myosin regulatory light chain 2 ventricular/cardiac muscle isoform
    • Regulatory light chain of myosin
    • RLC of myosin
    • Slow cardiac myosin regulatory light chain 2
    • ventricular/cardiac muscle isoform
    see all
  • 疾病相关Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic type 10 (CMH10) [MIM:608758]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 2 (MVC2) [MIM:608758]. MVC2 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
  • 序列相似性Contains 3 EF-hand domains.
  • 翻译后修饰N-terminus is methylated by METTL11A/NTM1.
  • Information by UniProt

Recombinant Human Myosin Light Chain 2 protein 图像

  • 15% SDS-PAGE showing ab79185 at approximately 21kDa (3µg).
  • All lanes : Anti-Myosin Light Chain 2 antibody [EPR3741] (ab92721) at 1/10000 dilution

    Lane 1 : Recombinant Human Myosin Light Chain 2 protein (ab79185) at 0.1 µg
    Lane 2 : Recombinant Human Myosin Light Chain 2 protein (ab79185) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 4 minutes

Recombinant Human Myosin Light Chain 2 protein (ab79185)参考文献

ab79185 has not yet been referenced specifically in any publications.

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