Recombinant人MYF6 protein (ab114698)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP23409
    • 种属Human
    • 序列MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPP EAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAAT
    • 分子量37 kDa including tags
    • 氨基酸1 to 99

技术指标

Our Abpromise guarantee covers the use of ab114698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • bHLHc4
    • Class C basic helix-loop-helix protein 4
    • CNM3
    • HERCULIN
    • MRF4
    • Muscle-regulatory factor 4
    • Muscle-specific regulatory factor 4
    • Myf-6
    • Myf6
    • MYF6_HUMAN
    • Myogenic factor 6
    • myogenic factor 6 (herculin)
    see all
  • 功能Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
  • 组织特异性Skeletal muscle.
  • 疾病相关Defects in MYF6 may be a cause of centronuclear myopathy autosomal dominant (ADCNM) [MIM:160150]; also known as autosomal dominant myotubular myopathy. Centronuclear myopathies are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers.
  • 序列相似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human MYF6 protein 图像

  • 12.5% SDS-PAGE showing ab114698 at approximately 36.52 kDa stained with Coomassie Blue.

Recombinant Human MYF6 protein (ab114698)参考文献

ab114698 has not yet been referenced specifically in any publications.

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