Recombinant人mtTFA protein (ab103784)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ00059
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMSSVLASCPKKPVSSYLRFSKEQLPIFKAQ NPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQL TPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQ EAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQ MIEVGRKDLLRRTIKKQRKYGAEEC
    • 分子量27 kDa including tags
    • 氨基酸43 to 246
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab103784 was purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • anscription factor 6-like 1
    • Mitochondrial transcription factor 1
    • mitochondrial transcription factor A
    • MtTF1
    • mtTFA
    • TCF 6
    • TCF-6
    • TCF6
    • TCF6L1
    • TCF6L2
    • TCF6L3
    • TFAM
    • TFAM_HUMAN
    • Transcription factor 6
    • Transcription factor 6 like 2
    • Transcription factor 6 like 2 (mitochondrial transcription factor)
    • Transcription factor 6-like 2
    • transcription factor 6-like 3
    • Transcription factor A, mitochondrial
    • Transcription factor A, mitochondrial precursor
    see all
  • 功能Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.
  • 序列相似性Contains 2 HMG box DNA-binding domains.
  • 细胞定位Mitochondrion.
  • Information by UniProt

Recombinant Human mtTFA protein 图像

  • 15% SDS-PAGE analysis of 3µg ab103784.

Recombinant Human mtTFA protein (ab103784)参考文献

ab103784 has not yet been referenced specifically in any publications.

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