Recombinant人MRG15 protein (ab124555)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9UBU8
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSHMAPKQD PKPKFQEGER VLCFHGPLLY EAKCVKVAIK DKQVKYFIHY SGWNKNWDEW VPESRVLKYV DTNLQKQREL QKANQEQYAE GKMRGAAPGK KTSGLQQKNV EVKTKKNKQK TPGNGDGGST SETPQPPRKK RARVDPTVEN EETFMNRVEV KVKIPEELKP WLVDDWDLIT RQKQLFYLPA KKNVDSILED YANYKKSRGN TDNKEYAVNE VVAGIKEYFN VMLGTQLLYK FERPQYAEIL ADHPDAPMSQ VYGAPHLLRL FVRIGAMLAY TPLDEKSLAL LLNYLHDFLK YLAKNSATLF SASDYEVAPP EYHRKAV
    • 分子量40 kDa including tags
    • 氨基酸1 to 323
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    Purified by using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol, 0.88% Sodium chloride

常规信息

  • 别名
    • CG6363
    • Eaf3
    • Esa1p associated factor 3 homolog
    • FWP006
    • HsT17725
    • MEAF3
    • MO4L1_HUMAN
    • MORF related gene on chromosome 15
    • MORF-related gene 15 protein
    • Morf4l1
    • MORFRG15
    • Mortality factor 4 like 1
    • Mortality factor 4 like protein 1
    • Mortality factor 4-like protein 1
    • MRG15
    • Protein MSL3-1
    • S863-6
    • Transcription factor-like protein MRG15
    see all
  • 功能Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
  • 序列相似性Belongs to the MRG family.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human MRG15 protein 图像

  • 15% SDS-PAGE analysis of ab124555 (3µg)

Recombinant Human MRG15 protein (ab124555)参考文献

ab124555 has not yet been referenced specifically in any publications.

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