Recombinant人MRCL3 protein (ab113139)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP19105
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGSHMSSKRTKTKTKKRPQRATSNVFAMFD QSQIQEFKEAFNMIDQNR DGFIDKEDLHDMLASLGKNPTDEYLDAMMN EAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE DYL RELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
    • 分子量22 kDa including tags
    • 氨基酸1 to 171
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab113139 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT

常规信息

  • 别名
    • ML12A_HUMAN
    • MLC 2B
    • MLC-2B
    • MLCB
    • MYL12A
    • Myosin regulatory light chain 12A
    • Myosin regulatory light chain 2
    • Myosin regulatory light chain 2, nonsarcomeric
    • Myosin regulatory light chain MRCL3
    • Myosin regulatory light chain MRLC3
    • Myosin RLC
    • Myosin, light polypeptide, regulatory, non sarcomeric (20kD)
    • nonsarcomeric
    • RLC
    see all
  • 功能Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
  • 序列相似性Contains 3 EF-hand domains.
  • 翻译后修饰Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge.
  • Information by UniProt

Recombinant Human MRCL3 protein 图像

  • 15% SDS-PAGE analysis of ab113139 (3µg)

Recombinant Human MRCL3 protein (ab113139)参考文献

ab113139 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"