Recombinant人MMP11 protein (ab92861)
- 数据表
- 具体的参考文献 (1)
- 实验方案
概述
- 产品名称Recombinant人MMP11 protein
- 蛋白长度Full length protein
描述
- 性质Recombinant
- 来源Escherichia coli
- 氨基酸序列
- 种属Human
相关产品
- Related Products
技术指标
Our Abpromise guarantee covers the use of ab92861 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 应用
SDS-PAGE
Western blot
ELISA
Mass Spectrometry
- 纯度> 90
% SDS-PAGE.
- 形式Liquid
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Concentration information loading...
制备和贮存
- 稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 100mM Imidazole
Constituents: 0.5M Sodium chloride, 20mM Tris HCl, 1mM Beta mercaptoethanol, pH 8.0
常规信息
-
别名
- Matrix Metalloproteinase 11
- Matrix metalloproteinase-11
- MMP-11
see all - 功能May play an important role in the progression of epithelial malignancies.
- 组织特异性Specifically expressed in stromal cells of breast carcinomas.
- 序列相似性Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains. - 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
- 翻译后修饰The precursor is cleaved by a furin endopeptidase.
- 细胞定位Secreted > extracellular space > extracellular matrix.
- Information by UniProt
Recombinant Human MMP11 protein 图像
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SDS-PAGE - MMP11 protein (Tagged-His Tag) (ab92861)10% SDS-PAGE stained with Coomassie Blue.
Recombinant Human MMP11 protein (ab92861)参考文献
This product has been referenced in:
- Roscilli G et al. Circulating MMP11 and specific antibody immune response in breast and prostate cancer patients. J Transl Med 12:54 (2014). Read more (PubMed: 24564996) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"