Recombinant人MLX protein (ab116726)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      LSVPRGCREDSSHPACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANSIG STSASSVPNTDDEDSDYHQEAYKESYKDRRRRAHTQAEQKRRDAIKRGYD
    • 分子量
      37 kDa including tags
    • 氨基酸
      50 to 150

技术指标

Our Abpromise guarantee covers the use of ab116726 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • bHLHd13
    • BigMax protein
    • Class D basic helix-loop-helix protein 13
    • MAD7
    • Max like bHLHZip protein
    • Max like protein X
    • Max-like bHLHZip protein
    • Max-like protein X
    • MLX
    • MLX_HUMAN
    • MLXIP
    • MONDOA
    • MXD7
    • Protein BigMax
    • Protein Mlx
    • TCFL4
    • transcription factor like 4
    • Transcription factor like protein 4
    • Transcription factor-like protein 4
    see all
  • 功能
    Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
  • 组织特异性
    Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung.
  • 序列相似性
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • 细胞定位
    Cytoplasm. Found predominantly in the cytoplasm and Nucleus. Found predominantly in the nucleus.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE showing ab116726 at approximately 36.63kDa.
    Stained with Coomassie Blue.

文献

ab116726 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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