Recombinant人MLK2 protein (ab125562)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ02779
    • 种属Human
    • 分子量76 kDa including tags
    • 氨基酸1 to 446

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技术指标

Our Abpromise guarantee covers the use of ab125562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity of ab125562 was determined to be 48 nmol/min/mg.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 纯度> 85 % Densitometry.
    Purity was determined to be >85% by densitometry.
  • 形式Liquid
  • 补充说明

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • M3K10_HUMAN
    • MAP3K 10
    • Map3k10
    • MEKK10
    • Mitogen activated protein kinase kinase kinase 10
    • Mitogen-activated protein kinase kinase kinase 10
    • Mixed lineage kinase 2
    • MKN28 derived nonreceptor type serine/threonine kinase
    • MKN28 kinase
    • MLK 2
    • MST
    • Protein kinase MST
    see all
  • 功能Activates the JUN N-terminal pathway.
  • 组织特异性Expressed in brain and skeletal muscle.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH3 domain.
  • 翻译后修饰Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.
  • Information by UniProt

Recombinant human MLK2 protein 图像

  • SDS-PAGE analysis of ab125562.
  • The specific activity of ab125562 was determined to be 48 nmol/min/mg by Kinase Assay.

Recombinant human MLK2 protein (ab125562)参考文献

ab125562 has not yet been referenced specifically in any publications.

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