Recombinant人MID1 protein (ab114762)

概述

  • 产品名称Recombinant人MID1 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO15344
    • 种属Human
    • 序列PNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDP KSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
    • 分子量37 kDa including tags
    • 氨基酸441 to 540

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BBBG 1
    • BBBG1
    • E3 ubiquitin-protein ligase Midline-1
    • Finger on X and Y mouse homolog of
    • FXY
    • GBBB 1
    • GBBB1
    • MID 1
    • Mid1
    • Midin
    • Midline 1
    • Midline 1 (Opitz/BBB syndrome)
    • Midline 1 ring finger
    • Midline 1 RING finger protein
    • Midline-1
    • Midline1
    • OGS 1
    • OGS1
    • OS
    • OSX
    • Putative transcription factor XPRF
    • RING finger protein 59
    • RING finger protein Midline-1
    • RNF 59
    • RNF59
    • TRI18
    • TRI18_HUMAN
    • TRIM 18
    • TRIM18
    • Tripartite motif containing protein 18
    • Tripartite motif protein TRIM18
    • Tripartite motif-containing protein 18
    • XPRF
    • zinc finger on X and Y, mouse, homolog of
    • Zinc finger X and Y
    • ZNFXY
    see all
  • 功能May have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation.
  • 组织特异性In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.
  • 疾病相关Defects in MID1 are the cause of Opitz syndrome type I (OS-I) [MIM:300000]. OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.
  • 序列相似性Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 B30.2/SPRY domain.
    Contains 1 COS domain.
    Contains 1 fibronectin type-III domain.
    Contains 1 RING-type zinc finger.
  • 翻译后修饰Phosphorylated on serine and threonine residues.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > spindle. Microtubule-associated. It is associated with microtubules throughout the cell cycle, co-localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodies during mitosis and cytokinesis.
  • Information by UniProt

Recombinant Human MID1 protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114762 at approximately 36.63kDa.

Recombinant Human MID1 protein (ab114762)参考文献

ab114762 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114762.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"