Recombinant人MGMT protein (ab79251)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEFP VPAFHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN

技术指标

Our Abpromise guarantee covers the use of ab79251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab79251 is purified using conventional chromatography techniques. Endotoxin Level:< 1.0 EU per 1 µg of protein (determined by LAL method)
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 7.5

常规信息

  • 别名
    • 6 O methylguanine DNA methyltransferase
    • 6-O-methylguanine-DNA methyltransferase
    • Agat
    • AGT
    • AI267024
    • EC 2.1.1.63
    • Methylated DNA protein cysteine methyltransferase
    • Methylated-DNA--protein-cysteine methyltransferase
    • Methylguanine DNA methyltransferase
    • MGC107020
    • MGMT
    • MGMT_HUMAN
    • O 6 methylguanine DNA alkyltransferase
    • O 6 methylguanine DNA methyltransferase
    • O-6-methylguanine-DNA methyltransferase
    • O-6-methylguanine-DNA-alkyltransferase
    see all
  • 功能Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  • 序列相似性Belongs to the MGMT family.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human MGMT protein (ab79251)参考文献

ab79251 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"