Recombinant人METTL1 protein (ab103495)

概述

  • 产品名称
    Recombinant人METTL1 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMAAETRNVAGAEAPPPQKRYYRQRAHSNPM ADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQAQVEF ADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRALRAAPAGG FQNIACLRSNAMKHLPNFFYKGQLTKMFFLFPDPHFKRTKHKWRIISPTL LAEYAYVLRVGGLVYTITDVLELHDWMCTHFEEHPLFERVPLEDLSEDPV VGHLGTSTEEGKKVLRNGGKNFPAIFRRIQDPVLQAVTSQTSLPGH
    • 分子量
      34 kDa including tags
    • 氨基酸
      1 to 276
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab103495 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • C12orf1
    • D1075 like gene product
    • FLJ95748
    • Methyltransferase like 1
    • Methyltransferase like protein 1
    • Methyltransferase-like protein 1
    • Mettl1
    • TRM8
    • TRMB_HUMAN
    • TRMT8
    • tRNA (guanine N(7) ) methyltransferase
    • tRNA (guanine(46)-N(7))-methyltransferase
    • tRNA (guanine-N(7)-)-methyltransferase
    • tRNA(m7G46) methyltransferase
    • tRNA(m7G46)-methyltransferase
    • YDL201w
    see all
  • 功能
    Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  • 组织特异性
    Ubiquitous.
  • 通路
    tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
  • 序列相似性
    Belongs to the methyltransferase superfamily. TrmB family.
  • 翻译后修饰
    Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of 3µg ab103495.

文献

ab103495 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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