- 来源Baculovirus infected Sf9 cells
- 分子量61 kDa including tags
- 氨基酸1 to 340
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 生物活性The Specific activity of ab102551 was determined to be 200 nmol/min/mg.
- 纯度> 85
Purity was determined to be >85% by densitometry.
ab204885 (ZIP Kinase peptide substrate) can be utilized as a substrate for assessing kinase activity
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 功能Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
- 组织特异性Expressed in placenta, kidney, thymus, testis, ovary and intestine.
- 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 KA1 (kinase-associated) domain.
Contains 1 protein kinase domain.
- 翻译后修饰Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.
Information by UniProt
Recombinant human MELK protein 图像
Recombinant human MELK protein (ab102551)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"