Recombinant人Melanoma Inhibitory Activity protein (ab73232)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列M-GPMPKLADRKLCADQECSSHPISMAVALQDYMAPDCRFLTIHRGQVV YVFSLKGRGRFLWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKVDVKT DKWDFYCQ.
    • 氨基酸25 to 131

技术指标

Our Abpromise guarantee covers the use of ab73232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Calculated by the inhibiting effect on the invasion of Mel In Tumor cells (Bosserhoff et al.2003 Lab Invest. 83, 1583-94).

  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    This protein was purified by proprietary chromatographic techniques. Purity greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Potassium phosphate, 150mM Potassium chloride, pH 7.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute in sterile 18Mohm-cm water to at not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

常规信息

  • 别名
    • Cartilage derived retinoic acid sensitive protein
    • CD RAP
    • CDRAP
    • Melanoma derived growth regulatory protein precursor
    • Melanoma inhibitory activity protein
    • Melanoma-derived growth regulatory protein
    • Mia
    • MIA_HUMAN
    see all
  • 功能Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
  • 组织特异性All malignant melanoma cell lines tested and infrequently in glioma cell lines.
  • 序列相似性Belongs to the MIA/OTOR family.
    Contains 1 SH3 domain.
  • 翻译后修饰May possess two intramolecular disulfide bonds.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Melanoma Inhibitory Activity protein (ab73232)参考文献

ab73232 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"