重组人CD167a/DDR1蛋白(ab101591)
Key features and details
- Expression system: Baculovirus infected insect cells
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, WB, SDS-PAGE
描述
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产品名称
重组人CD167a/DDR1蛋白
参阅全部 CD167a/DDR1 蛋白酶 -
生物活性
The specific activity of CD167a/DDR1 is determined to be 5 nmol/min/mg
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纯度
> 90 % SDS-PAGE.
The purity was determined to be >90% by densitometry. Affinity purified. -
表达系统
Baculovirus infected insect cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
77 kDa including tags -
氨基酸
444 to 876
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相关产品
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Substrate reagent
技术指标
Our Abpromise guarantee covers the use of ab101591 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
Western blot
SDS-PAGE
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形式
Liquid -
补充说明
ab204867 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity
This product was previously labelled as MCK10
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- CAK
- CD 167
- CD167
see all -
功能
May be involved in cell-cell interactions and recognition. -
组织特异性
Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin. -
序列相似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Contains 1 F5/8 type C domain.
Contains 1 protein kinase domain. -
结构域
The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates. -
细胞定位
Secreted and Membrane. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab101591 尚未被引用在任何文献中。