Recombinant人MCK10 protein (ab101591) (ab101591)

概述

  • 产品名称
    Recombinant人MCK10 protein (ab101591)
    参阅全部 MCK10 蛋白酶
  • 蛋白长度
    Protein fragment
  • 描述
    Recombinant人MCK10 protein

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      77 kDa including tags
    • 氨基酸
      444 to 876

相关产品

技术指标

Our Abpromise guarantee covers the use of ab101591 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    The specific activity of MCK10 is determined to be 5 nmol/min/mg
  • 应用

    Functional Studies

    Western blot

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    The purity was determined to be >90% by densitometry
  • 形式
    Liquid
  • 补充说明

    ab204867 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • CAK
    • CD 167
    • CD167
    • CD167 antigen-like family member A
    • CD167a
    • Cell adhesion kinase
    • DDR
    • DDR 1
    • DDR1
    • DDR1_HUMAN
    • Discoidin domain receptor
    • Discoidin domain receptor tyrosine kinase 1
    • Discoidin receptor tyrosine kinase
    • Discoidin receptor tyrosine kinase isoform a
    • EDDR 1
    • EDDR1
    • Epithelial discoidin domain receptor 1
    • Epithelial discoidin domain-containing receptor 1
    • Epithelial specific receptor kinase
    • HGK2
    • Mammarian carcinoma kinase 10
    • Mammary carcinoma kinase 10
    • MCK-10
    • MCK10
    • NEP
    • Neuroepithelial tyrosine kinase
    • Neurotrophic tyrosine kinase receptor type 4
    • NTRK 4
    • NTRK4
    • OTTHUMP00000029343
    • OTTHUMP00000029344
    • OTTHUMP00000029345
    • OTTHUMP00000029346
    • OTTHUMP00000029347
    • OTTHUMP00000164863
    • OTTHUMP00000164867
    • OTTHUMP00000222080
    • Protein-tyrosine kinase 3A
    • Protein-tyrosine kinase RTK-6
    • PTK 3
    • PTK 3A protein tyrosine kinase 3A
    • PTK3
    • PTK3A
    • Receptor tyrosine kinase NEP
    • RTK 6
    • RTK6
    • TRK E
    • TRKE
    • Tyrosine kinase DDR
    • Tyrosine kinase receptor E
    • Tyrosine-protein kinase CAK
    see all
  • 功能
    May be involved in cell-cell interactions and recognition.
  • 组织特异性
    Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.
  • 序列相似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 F5/8 type C domain.
    Contains 1 protein kinase domain.
  • 结构域
    The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates.
  • 细胞定位
    Secreted and Membrane.
  • Information by UniProt

Recombinant human MCK10 protein (ab101591) 图像

  • SDS-PAGE analysis of ab101591
  • Specific activity of ab101591

Recombinant human MCK10 protein (ab101591) (ab101591)参考文献

ab101591 has not yet been referenced specifically in any publications.

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