重组人MC2 receptor蛋白(ab152516)

概述

  • 产品名称
    重组人MC2 receptor蛋白
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVV LTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLA RSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPY CACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
    • 分子量
      60 kDa including tags
    • 氨基酸
      1 to 297

技术指标

Our Abpromise guarantee covers the use of ab152516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ACTH receptor
    • ACTH-R
    • ACTHR
    • ACTHR_HUMAN
    • Adrenocorticotropic hormone receptor
    • Adrenocorticotropin receptor
    • Corticotropin receptor
    • MC2 receptor
    • MC2-R
    • MC2R
    • Melanocortin 2 receptor
    • Melanocortin 2 receptor (adrenocorticotropic hormone)
    • Melanocortin receptor 2
    see all
  • 功能
    Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase.
  • 组织特异性
    Melanocytes and corticoadrenal tissue.
  • 疾病相关
    Defects in MC2R are the cause of glucocorticoid deficiency type 1 (GCCD1) [MIM:202200]; also known as familial glucocorticoid deficiency type 1 (FGD1). GCCD1 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152516 stained with Coomassie Blue.

文献

ab152516 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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