重组人MC1 Receptor蛋白(ab152515)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGL VSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILL LEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYAL RYHSTVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAML VLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIF FLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF HSQELRRTLKEVLTCSW
    • 分子量
      61 kDa including tags
    • 氨基酸
      1 to 317

相关产品

技术指标

Our Abpromise guarantee covers the use of ab152515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CMM5
    • MC1-R
    • MC1R
    • Melanocortin 1 receptor
    • Melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
    • Melanocortin receptor 1
    • Melanocyte-stimulating hormone receptor
    • Melanotropin receptor
    • MSH-R
    • MSHR
    • MSHR_HUMAN
    • SHEP2
    see all
  • 功能
    Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
  • 组织特异性
    Melanocytes and corticoadrenal tissue.
  • 疾病相关
    Genetic variations in MC1R are a cause of susceptibility to cutaneous malignant melanoma type 5 (CMM5) [MIM:613099]. Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152515 stained with Coomassie Blue.

文献

ab152515 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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