Recombinant人MAPKAP Kinase 2 protein (ab79910)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab79910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

    Western blot

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 138mM Sodium chloride, pH 8

常规信息

  • 别名
    • MAP kinase activated protein Kinase 2
    • MAP kinase-activated protein kinase 2
    • MAPK activated protein kinase 2
    • MAPK-activated protein kinase 2
    • MAPK2_HUMAN
    • MAPKAP K2
    • MAPKAP kinase 2
    • MAPKAPK 2
    • MAPKAPK-2
    • MAPKAPK2
    • Mitogen activated protein kinase activated protein kinase 2
    • MK 2
    • MK2
    see all
  • 功能Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.
  • 组织特异性Expressed in all tissues examined.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated and activated by MAP kinase.
  • Information by UniProt

Recombinant Human MAPKAP Kinase 2 protein 图像

  • Lane 1: ab79910 on 10% SDS-PAGE, Coomassie staining, 7µg.
    Lane 2: Protein marker.
  • All lanes : Anti-MAPKAP Kinase 2 antibody (ab63574) at 1/500 dilution

    Lane 1 : Recombinant Human MAPKAP Kinase 2 protein (ab79910) at 0.01 µg
    Lane 2 : Recombinant Human MAPKAP Kinase 2 protein (ab79910) at 0.001 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 90 seconds

Recombinant Human MAPKAP Kinase 2 protein (ab79910)参考文献

ab79910 has not yet been referenced specifically in any publications.

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