Recombinant人MAPK11 protein (ab117219)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ15759
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGSMSGPRAGFYRQELNKTVWEVPQRLQGL RPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKH LKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHV QFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADE EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSD YIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGA NPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESV EAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
    • 分子量44 kDa including tags
    • 氨基酸1 to 364
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab117219 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab117219 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • Human p38Beta MAP kinase mRNA complete cds
    • MAP kinase 11
    • MAP kinase p38 beta
    • MAPK 11
    • Mapk11
    • Mitogen activated protein kinase 11
    • Mitogen activated protein kinase p38 2
    • Mitogen activated protein kinase p38 beta
    • Mitogen-activated protein kinase 11
    • Mitogen-activated protein kinase p38 beta
    • MK11_HUMAN
    • p38 2
    • p38-2
    • p38B
    • p38Beta
    • P38BETA2
    • PRKM11
    • Protein kinase mitogen activated 11
    • SAPK2
    • SAPK2B
    • Stress activated protein kinase 2
    • Stress activated protein kinase 2b
    • Stress-activated protein kinase 2
    see all
  • 功能Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.
  • 组织特异性Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • 结构域The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • 翻译后修饰Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
  • Information by UniProt

Recombinant Human MAPK11 protein 图像

  • 15% SDS-PAGE showing ab117219 at approximately 43.8kDa (3µg).

Recombinant Human MAPK11 protein (ab117219)参考文献

ab117219 has not yet been referenced specifically in any publications.

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