Recombinant人MAP4K6 protein (ab55712)

概述

  • 产品名称Recombinant人MAP4K6 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 氨基酸1 to 320

技术指标

Our Abpromise guarantee covers the use of ab55712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific Activity: 19 nmol/min/mg
  • 应用

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • B55
    • GCK family kinase MiNK
    • hMINK
    • Map4k6
    • MAPK/ERK kinase kinase kinase 6
    • MEK (MAP/ERK) kinase kinase 6
    • MEK kinase kinase 6
    • MEKKK6
    • MGC21111
    • MINK
    • MINK 1
    • MINK1
    • Misshapen like kinase 1
    • Misshapen NIKs Related kinase
    • Misshapen/NIK related kinase
    • Mitogen activated protein kinase kinase kinase kinase 6
    • RP23-122P1.6
    • Ysk2
    • ZC3
    see all
  • 相关性MAP4K6 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. These kinases regulate a wide variety of cellular processes by coupling cell surface receptors to MAPK pathways. This kinase appears to act upstream of the JUN N-terminal pathway and may be involved in brain development. It may also play a role in the response to environmental stress, in cytoskeleton reorganization, cell adhesion, and cell motility. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
  • 细胞定位Cytoplasm. Cell junction; synapse; postsynaptic cell membrane; postsynaptic density. Cell projection; axon. Cell projection; dendrite. Isoform 4: Golgi apparatus

Recombinant human MAP4K6 protein 图像

  • SDS-PAGE analysis of ab55712 with molecular weight markers. Approximate molecular weight 61kDa.
  • Kinase assay using ab55712. Specific activity: 19 nmol/min/mg.

Recombinant human MAP4K6 protein (ab55712)参考文献

ab55712 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55712.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"