Recombinant人MAP4K1 protein (ab107953)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus infected Sf9 cells
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      65 kDa including tags
    • 氨基酸
      1 to 346

技术指标

Our Abpromise guarantee covers the use of ab107953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    The Specific activity of ab107953 was determined to be 125 nmol/min/mg.
  • 应用

    SDS-PAGE

    Western blot

    Functional Studies

  • 纯度
    > 75 % SDS-PAGE.
    Purity was determined to be >75% by densitometry.
  • 形式
    Liquid
  • 补充说明

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Hematopoietic progenitor kinase
    • Hematopoietic progenitor kinase 1
    • HPK1
    • Human Hematopoietic Progenitor Kinase
    • M4K1_HUMAN
    • Map4k1
    • MAPK/ERK kinase kinase kinase 1
    • MEK kinase kinase 1
    • MEKKK 1
    • Mitogen activated protein kinase kinase kinase kinase 1
    • Mitogen-activated protein kinase kinase kinase kinase 1
    see all
  • 功能
    May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.
  • 组织特异性
    Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CNH domain.
    Contains 1 protein kinase domain.
  • Information by UniProt

图片

  • SDS-PAGE showing ab107953 at approximately 65kDa.
  • Kinase Assay demonstrating specific activity of ab107953.

文献

ab107953 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for contacting us. The tag for this protein is a GST tag. Please let me know if I can be of further assistance.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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