Recombinant人MAP2K1IP1 protein (ab102022)

概述

  • 产品名称
    Recombinant人MAP2K1IP1 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMADDLKRFLYKKLPSVEGLHAIVVSDRDGV PVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQV VQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS
    • 分子量
      16 kDa including tags
    • 氨基酸
      1 to 124
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab102022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 95 % SDS-PAGE.
    ab102022 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 5mM DTT, 20mM Tris HCl, 100mM Sodium chloride, pH 8.0

常规信息

  • 别名
    • LAMTOR3
    • Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
    • LTOR3_HUMAN
    • MAP2K1IP1
    • MEK binding partner 1
    • MEK partner 1
    • MEK-binding partner 1
    • Mitogen activated protein kinase kinase 1 interacting protein 1
    • Mitogen-activated protein kinase kinase 1-interacting protein 1
    • Mitogen-activated protein kinase scaffold protein 1
    • Mp1
    • Ragulator complex protein LAMTOR3
    see all
  • 功能
    As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
  • 序列相似性
    Belongs to the LAMTOR3 family.
  • 细胞定位
    Late endosome membrane.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of 3µg ab102022.

文献

ab102022 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab102022.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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