Recombinant人MAP2 protein (ab114686)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP11137-2
    • 种属Human
    • 序列MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPY REDEEGAFGEHGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTA EAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVE EAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTP PSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTS KCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVK IDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLL ESPQLATLAEDVTAALAKQGL
    • 分子量78 kDa including tags
    • 氨基酸1 to 471

技术指标

Our Abpromise guarantee covers the use of ab114686 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • DKFZp686I2148
    • MAP 2
    • MAP dendrite specific
    • MAP-2
    • MAP2
    • MAP2A
    • MAP2B
    • MAP2C
    • Microtubule associated protein 2
    • Microtubule-associated protein 2
    • MTAP2_HUMAN
    see all
  • 功能The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
  • 序列相似性Contains 3 Tau/MAP repeats.
  • 翻译后修饰Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67.
  • 细胞定位Cytoplasm, cytoskeleton.
  • Information by UniProt

Recombinant Human MAP2 protein 图像

  • ab114686 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human MAP2 protein (ab114686)参考文献

ab114686 has not yet been referenced specifically in any publications.

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