Recombinant人MAP1LC3A protein (ab92050)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      DRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKF LVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQ EKDEDGFLYMVYASQETFGF
    • 氨基酸
      4 to 121

技术指标

Our Abpromise guarantee covers the use of ab92050 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5

  • 复溶
    Reconstitute with 108 µl aqua dest.

常规信息

  • 别名
    • ATG8E
    • Autophagy-related protein LC3 A
    • Autophagy-related ubiquitin-like modifier LC3 A
    • LC3
    • LC3A
    • MAP1 light chain 3 like protein 1
    • MAP1 light chain 3-like protein 1
    • MAP1A/1B light chain 3 A
    • MAP1A/MAP1B LC3 A
    • MAP1A/MAP1B light chain 3 A
    • MAP1ALC3
    • MAP1BLC3
    • Map1lc3a
    • Microtubule associated proteins 1A/1B light chain 3
    • Microtubule-associated protein 1 light chain 3 alpha
    • Microtubule-associated proteins 1A and 1B, light chain 3
    • Microtubule-associated proteins 1A/1B light chain 3A
    • MLP3A_HUMAN
    see all
  • 功能
    Probably involved in formation of autophagosomal vacuoles (autophagosomes).
  • 组织特异性
    Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
  • 序列相似性
    Belongs to the MAP1 LC3 family.
  • 翻译后修饰
    The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
  • 细胞定位
    Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.
  • Information by UniProt

图片

  • The image shows an electrophoretic assay performed using an Agilent 5100 ALP. A coloured control band can be seen at 15 kDa (green). The protein-specific band is blue.

文献

ab92050 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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