Recombinant人MAGE 1 protein (ab75539)

概述

  • 产品名称Recombinant人MAGE 1 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 分子量60 kDa including tags

技术指标

Our Abpromise guarantee covers the use of ab75539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性MAGE 1 antibody reactive.
  • 应用

    Western blot

    ELISA

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Antigen MZ2 E
    • Antigen MZ2-E
    • Cancer/testis antigen 1.1
    • cancer/testis antigen family 1, member 1
    • CT1.1
    • MAGA1_HUMAN
    • MAGE 1 antigen
    • MAGE-1 antigen
    • MAGE1
    • MAGE1A
    • MAGEA1
    • Melanoma antigen 1
    • Melanoma antigen family A 1
    • Melanoma antigen family A 1 (directs expression of antigen MZ2 E)
    • Melanoma antigen MAGE 1
    • Melanoma associated antigen 1
    • Melanoma associated antigen MZ2 E
    • Melanoma-associated antigen 1
    • MGC9326
    see all
  • 功能May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
  • 组织特异性Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
  • 序列相似性Contains 1 MAGE domain.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant human MAGE 1 protein (ab75539)参考文献

ab75539 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"