Recombinant人MAFG protein (ab113589)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO15525
    • 种属Human
    • 分子量20 kDa including tags
    • 氨基酸1 to 162
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab113589 was purified by using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • AA545192
    • Basic leucine zipper transcription factor MafG
    • C630022N07Rik
    • hMAF
    • MAFG
    • MAFG v maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
    • MAFG_HUMAN
    • MGC13090
    • MGC20149
    • RP23 84C12.9
    • Transcription factor MafG
    • V maf musculoaponeurotic fibrosarcoma oncogene homolog G
    • V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
    see all
  • 功能Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+).
  • 组织特异性Highly expressed in skeletal muscle. Also expressed in heart and brain.
  • 序列相似性Belongs to the bZIP family. Maf subfamily.
    Contains 1 bZIP domain.
  • 翻译后修饰Acetylated in erythroid cells by CREB-binding protein (CBP). Acetylation augments the DNA-binding activity of NFE2, but has no effect on binding NFE2.
    Sumoylation at Lys-14 is required for active transcriptional repression.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human MAFG protein 图像

  • ab113589 at 3 µg analysed by 15% SDS-PAGE.

Recombinant Human MAFG protein (ab113589)参考文献

ab113589 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113589.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"