The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 0.100 Eu/µg
The biological activity of this product was determined by its ability to chemoattract human T-cells using a concentration range of 1.0-10.0 ng/ml.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Alternative macrophage activation associated CC chemokine 1
Alternative macrophage activation-associated CC chemokine 1
CC chemokine PARC
Dendritic cell chemokine 1
Macrophage inflammatory protein 4
Pulmonary and activation regulated chemokine
Pulmonary and activation-regulated chemokine
Small inducible cytokine A18
Small-inducible cytokine A18
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid.
Belongs to the intercrine beta (chemokine CC) family.