Recombinant人Macrophage Inflammatory Protein 3 alpha (ab125762)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      8 kDa
    • 氨基酸
      27 to 96

技术指标

Our Abpromise guarantee covers the use of ab125762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml.
  • 应用

    SDS-PAGE

    HPLC

    Functional Studies

  • 纯度
    > 97 % SDS-PAGE.
    >97% by SDS-PAGE and HPLC analyses
  • 形式
    Lyophilised
  • 补充说明
    Reconstituted ab125762 should be stored in working aliquots at -20°C. Avoid freeze/thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml. Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers.

常规信息

  • 别名
    • Beta-chemokine exodus-1
    • C C motif chemokine ligand 20
    • C-C motif chemokine 20
    • CC chemokine LARC
    • Ccl20
    • CCL20(2-70)
    • CCL20_HUMAN
    • Chemokine (C C motif) ligand 20
    • Chemokine CC motif ligand 20
    • CKb4
    • Exodus
    • Exodus 1
    • LARC
    • Liver and activation-regulated chemokine
    • Macrophage inflammatory protein 3 alpha
    • MIP 3 alpha
    • MIP 3A
    • MIP-3-alpha
    • MIP-3a
    • MIP3A
    • SCYA20
    • Small inducible cytokine A20
    • Small inducible cytokine subfamily A (Cys Cys) member 20
    • Small-inducible cytokine A20
    • ST38
    see all
  • 功能
    Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
  • 组织特异性
    Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
  • 序列相似性
    Belongs to the intercrine beta (chemokine CC) family.
  • 翻译后修饰
    C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • 细胞定位
    Secreted.
  • Information by UniProt

Recombinant human Macrophage Inflammatory Protein 3 alpha (ab125762)参考文献

ab125762 has not yet been referenced specifically in any publications.

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