Recombinant人LXR alpha protein (ab81934)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 氨基酸215 to 667

技术指标

Our Abpromise guarantee covers the use of ab81934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性1 unit equals 1 nanogram purified protein.
  • 应用

    SDS-PAGE

    EMSA

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • 补充说明1 unit equals 1 nanogram purified protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

常规信息

  • 别名
    • Liver X receptor alpha
    • LXR a
    • LXRA
    • NR1H3
    • NR1H3_HUMAN
    • Nuclear receptor subfamily 1 group H member 3
    • Oxysterols receptor LXR alpha
    • Oxysterols receptor LXR-alpha
    • RLD 1
    • RLD1
    see all
  • 功能Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • 组织特异性Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human LXR alpha protein (ab81934)参考文献

ab81934 has not yet been referenced specifically in any publications.

Product Wall

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this h...

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Apologies for delay. We unfortunately cannot confirm the protein - the error happened due to mislabelling of the product. It seems there might be LXR beta in it however I can not 100% confirm it but surely it is not L...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"